Review of the contraceptive drug Depo-Provera for cats

Spring or any other period of sexual activity in unspayed/non-sterilized cats is a turbulent time not only for the animals themselves, but also for their owners. Animals become more excitable and restless, and their endless guttural screams will drive anyone crazy. Cats mark their territory, cats roll on the floor and purr invitingly.

There are two ways to stop this phenomenon: the best option is sterilization or, as an alternative but temporary solution, hormonal drugs in the form of tablets or drops. For lack of opportunity, or perhaps due to lack of desire, you can choose a remedy for your pet’s wanderings.

special instructions

Before prescribing Depo-Provera, the patient should be thoroughly examined.
If signs and/or symptoms of thromboembolism occur, the risk-benefit ratio should be assessed before continuing use of the drug.

If the Itsenko-Cushing symptom complex (moon face, fluid retention, decreased glucose tolerance, increased blood pressure) appears while taking the drug in high doses, the dose should be reduced if possible and the patient's condition should be carefully monitored.

Use of the drug in high doses may cause weight gain and fluid retention

Therefore, caution should be exercised when treating patients who may be adversely affected by weight gain or fluid retention.

Patients with a history of treatment for depression should be carefully monitored. During therapy with Depo-Provera, some patients complain of depression similar to premenstrual depression.

When conducting a cytological or histological examination of the endometrium or cervix, it is necessary to notify the histologist about the therapy being carried out.

The drug should be used with caution in the postpartum period due to the increased risk of heavy and prolonged uterine bleeding. It is believed that the use of Depo-Provera may increase the risk of developing osteoporosis.

It is believed that the use of Depo-Provera may increase the risk of developing osteoporosis.

You should stop using the drug if there is a sudden partial or complete loss of vision, or if you develop bulging eyes, double vision, or migraine attacks. If the examination reveals damage to the fiber vessels or swelling of the optic nerve nipple, Depo-Provera should also not be used.

If jaundice develops, you must stop using the drug.

The use of the drug may affect the results of the following laboratory tests: determination of gonadotropin levels (downward); determination of blood plasma levels of progesterone, cortisol, estrogens (towards a decrease); determination of the level of pregnanediol in urine (downward); determination of testosterone levels in blood plasma (towards a decrease); determination of the level of specific globulin that binds sex hormones (towards a decrease); performing a sugar load test (glucose tolerance test); metapyrone test; can change the results of the test for prothrombin (factor II) and blood clotting factors VII, VIII, IX, X (increasing); increases the value of liver function indicators.

AN INJECTION FOR A CAT SO YOU DON'T ASK THE CAT WHEN IT'S A WAY OUT

There are cases when the so-called injection of a cat from a party is the only way out, but they are rare. Such cases include all sorts of contraindications to surgery. For example, a cat has a weak heart or kidneys, and therefore cannot be given anesthesia. It is impossible to carry out a sterilization operation without general anesthesia, so the only thing left is to endure the heat, or give injections, or give hormonal pills.

Sometimes this is practiced in nurseries, because... cats should not become pregnant every time they are in heat, and for some, the condition is so debilitating that breeders may resort to the last resort of injecting the drug.

But in any case, such things must be done strictly under the supervision of a veterinarian, who will select the right drug, the right dosage and the correct injection schedule.

– this is always a difficult period for both the owners and the pet itself. Therefore, the owner often resorts to various measures to eliminate unpleasant, but so often inevitable symptoms. One of the effective ways to make life easier for yourself and your pet is to give her a hormonal injection. However, how simple is it, and does your pet really need this injection? Let's try to figure it out together.

Indications for use

Indications for the use of hormonal contraception in cats are the need to prevent estrus once or the need to constantly eliminate it in the case when the cat cannot be sterilized due to contraindications to surgery.

Indications for the use of hormonal contraception in cats are the need to prevent estrus once

The drug is also prescribed if during the operation, at the owner’s request, the tubes were only tied, and after a while the estrus resumed again. Sterilization may be prohibited in case of severe pathologies of the cat’s liver, kidneys and heart, as well as in cases of intolerance to anesthesia.

Be sure to read:

At what age is it better to adopt a kitten: when is it possible, why can’t it be taken early, what are the dangers

In rare cases, the drug is included in the complex therapy of uterine tumors. Such treatment requires constant monitoring by a veterinarian and does not allow the pet to prescribe the drug independently.

At what age and in what dosage it is permissible to use the drug for each specific animal should be determined by a veterinarian. Unauthorized use of hormonal drugs poses a serious danger to the cat.

Side effects of the drug

For those cat owners who want to find a “magic” remedy to prevent heat, it is important to know that such drugs may not be completely safe. In addition to the fact that you need to follow special rules when performing an injection, you should carry out treatment only after consultation with a specialist

He will warn you how Covinan can be dangerous for cats. Side effects do not occur so often, but they are quite unpleasant for both the animal and its owner:

• Many cats have an increased appetite and begin to gain weight;
• some owners note lethargy and lethargy of the animal after treatment;
• the mammary glands may enlarge and even develop a tumor;
• sometimes purulent inflammation of the uterus occurs;
• the activity of the endocrine system may be disrupted;
• local reactions include hair loss or lightening at the injection site.

Alternative to injections for estrus

Suprelorin

- a peptide-based contraceptive implant containing the active substance deslorelin. It is used for temporary castration of animals with the possibility of restoring reproductive function. The implant is inserted subcutaneously, a slow release of the hormone occurs, suppressing the production of pituitary hormones and, accordingly, sex hormones. This leads first to a sharp increase in sexual activity, and then to its complete suppression. The effect is achieved 6 weeks after insertion of the implant and lasts in cats for an average of 6 to 24 months.

The implant size is only 2.3 by 12.5 mm. It is located in the needle of a syringe-pusher, with which the doctor inserts the implant into the cat’s withers. The procedure is simple and safe, it is carried out by analogy with. Of the side effects of this drug, only a local reaction of the injection site is described: swelling, inflammation, which, as a rule, go away on their own.

Although the drug is currently only licensed for dogs and ferrets, its use in cats is gaining momentum. Suprelorin has established itself as the safest method of hormonal contraception in these animals.

Restrictions:

This contraceptive is not recommended for use in young cats that have not reached puberty, as there are not enough studies yet to confirm its safety in this category.

TOP innovative drugs for cats against partying

To select the correct drug, you need to show your pet to a veterinarian. He will examine the animal and suggest the most gentle regimen for using tablets/drops.

Pills

Veterinarians believe that the tablets are highly effective. They very quickly relieve sexual desire in cats. Their active substance is quickly eliminated from the body. This process lasts from 24 hours to 2 weeks.

Four with a tail

The cost of tablets is 55 rubles. In terms of their effectiveness, they are not inferior to more expensive options. However, finding them in veterinary pharmacies is not so easy. Therefore it is not very common. Tablets are started to be given to the pet in the first days of sexual activity. They relieve the condition in cats well and relieve aggression in cats. It has a pronounced effect on the animal body. Its composition is similar to its competitors.

There are not enough reviews about the tablets because they are not widespread. However, people who used them for their pets were satisfied. They consider “Four and a Tail” to be effective, not inferior in impact to their expensive counterparts. No side effects were observed in cats.

tablets four with a tail

Advantages:

• low cost;
• high efficiency;
• no side effects.

Flaws:

• difficult to get in pharmacies.

EX-7.5

You can buy such tablets for 216 rubles. You can also find a suspension on sale. Designed for dogs and cats of both sexes. The product is patented and will not harm the animal. It is made on the basis of megestrol. This hormone is considered one of the safest. It perfectly suppresses the sexual function of animals. The pet will lose aggression and anxiety. There are no side effects. The only thing that can happen is an individual intolerance to the pills.

Despite the absence of side effects, long-term use can cause excess weight and enlargement of the animal's mammary glands. Users do not question the effectiveness of EX-7.5. There are many positive reviews about it. However, many believe that long-term use of tablets can be harmful to the health of the animal.

EX-7.5 tablets

Advantages:

• high efficiency;
• products are patented.

Flaws:

• not found.

Stop intimate

Price - 153 rubles. It is intended to suppress the sexual function of cats. In animals, after consuming the drops, attraction and activity decrease, and aggression disappears. Before use, you must carefully read the instructions. This is necessary to achieve the desired result. After all, the procedure for taking the drug for cats and cats has significant differences. If you give your pet the wrong dosage, the effectiveness will be very weak. The frequency of administration is also of great importance.

There are many positive reviews about the medicine on the Internet. Pet owners write that it effectively helps animals overcome the period associated with sexual desire. The tablets calm cats and cats. The animals behave appropriately. However, many warn that the product should not be used for an extended period of time. This is due to side effects. After all, all hormonal drugs have an effect on the body. Users recommend using it as needed.

Stop intimate tablets

Advantages:

• the product is one of the most versatile;
• After application, the animal behaves correctly.

Flaws:

• not found.

Counter NEO

Cost - 100 rubles. You can buy it in tablets and liquid form. This allows pet owners to choose the optimal dosage regimen. The tablets are very small in size and the drops have no taste. Therefore, pets will take the drug without problems. In reviews, owners indicate that the product quickly affects the animal’s body. The effect is visible already on the second day. The animal loses all signs of sexual activity. The manufacturer demonstrates its products as safe and have no harmful effects on the animal’s body. Buyers most often purchase the drug in liquid form. Four drops are enough for one dose. However, the weight of the pet must be taken into account.

Pet owners note that the drug begins to act very quickly. The pets' behavior returns to normal the next day. They stop screaming and asking to go outside. Cats that marked their territory stop leaving their marks on things. Has a contraceptive effect and eliminates unnecessary pregnancy.

Counter NEO

Advantages:

• the price corresponds to the quality of the product;
• rapid impact on the animal’s body;
• high security.

Flaws:

• not found.

Gestrenol

You can buy Gestrenol for 150 rubles. It has a strong effect, suppresses the reproduction function of animals. In cats and kittens, sexual desire ceases. The pills will also prevent unnecessary pregnancy. For cats and cats they are produced separately. It is given in small courses, which last 4-5 days. Such a short period eliminates the occurrence of side effects in animals.

If we take into account the number of reviews, it turns out that this drug is purchased by pet owners most often. They consider it a strong and effective drug. It is available not only in tablets, but also in drops.

Proper use gives positive results. Animals behave quietly and calmly. The effect is ensured from the 1st day of use. Cats lose aggression. The pets stop meowing loudly and calling their partners to mate. Users consider the product a lifesaver during the mating season for pets.

Gestrenol tablets

Advantages:

• one of the best;
• no side effects;
• Available in drops and tablets.

Flaws:

• not detected.

Grass and briquettes

Mating-minus

You can buy it at the pharmacy for 135 rubles. Safe because it does not contain hormones. Made from medicinal herbs. It can be taken for a long time without harm to health. Gently affects the sexual function of cats and kittens, corrects their behavior and condition. Manufacturers claim that it stops cycles in cats.

However, some users write in their reviews about a weak effect. They claim that it does not stop the cycle in pets. Otherwise, the tablets are good, they can be used to regulate the behavior of animals. They will stop harsh screams, inappropriate behavior and territory marking. The drug is available in tablets and liquid form. This gives a certain freedom of action. The liquid is easy to mix into food. The pet will eat it without even noticing the catch.

Mating-minus

Advantages:

• highest security;
• the composition does not contain hormones.

Flaws:

• not found.

Pillkan

Such products cost 450 rubles. The product can delay or completely interrupt the cycle in cats. The animal will behave correctly. It will relieve its owners from loud meows and territory markings. Manufacturers produce the drug in the form of sugared cubes. Therefore, they can be fed whole to pets or added to food. It is given to pets according to a special scheme. It is not recommended to use it more than twice a year. The maximum duration of the course is one month.

The drug contains hormones. Its effectiveness is quite high. However, it is not widespread. It has a rather high price and the products cannot be found in every pharmacy. There are many positive reviews on the Internet. Users write that the drug does its job well. They consider it one of the best remedies for suppressing the sexual function of cats.

Pillkan

Advantages:

• An excellent drug for stopping the cycle in cats and suppressing aggressive behavior in cats.

Flaws:

• high price;
• The drug is difficult to find in city pharmacies.

Injections

Hormone injections are allowed to be used only in difficult cases, since they are considered “heavy artillery”. Do not forget that the use of hormones must be agreed with a specialist, since only a veterinarian can select a hormonal drug for a cat, the required dosage and number of injections.

Cowinan

The drug is a solution containing hormones and is prescribed to females to stop estrus, prevent pseudolactation or false pregnancy. In order for the female to behave calmly, one injection is needed every six months.

But it is necessary to take into account the multiple side effects and contraindications of the drug. Pregnant and lactating females, animals with diabetes and diseases of the genitourinary system should not be administered the drug. Side effects include endometritis, apathy, pyometritis, breast tumors and even depression.

Cowinan

Advantages:

• one injection every six months;
• pronounced effect.

Flaws:

• many contraindications and side effects.

Drops

Preparations available in the form of drops are much more convenient than tablets, since they are easier to give to animals - you just need to drop a drop on the cat’s nose or tongue. Each pet store has an assortment of hormonal drops against cat walking “Antisex”, STOP INTIM”, “SEX BARRIER”. The packaging of each drug is provided with detailed instructions, but before you start using it, you must consult a veterinarian and agree with him on the dosage regimen.

Ovostop

Quite expensive compared to other similar products, but easy to use and effective drug with a universal multicomponent composition, which includes melatonin, proroxan and megestrol. These components together perfectly calm cats, negating all manifestations of festivities. Pets sleep a lot after taking the drug in order to recover faster from stress. A great convenience is that Ovostop must be applied once and somewhat unconventionally - in the form of drops on the withers. The drug has a fairly long-term contraceptive effect: in the warm season, estrus does not begin for 2-3 months, in the cold season - up to six months.

Users respond generally positively to the drug, especially noting its convenient use compared to other drugs. The effectiveness is also noted positively, however, some users believe that the manufacturer exaggerates the stated duration of action, since the drug stops working earlier.

Ovostop drops

Advantages:

• easy to use;
• effectively calms animals.

Flaws:

• The validity period stated by the manufacturer is exaggerated.

SexCONTROL

A standard hormonal agent that is used to stop estrus in cats during periods of partying, to prevent unwanted pregnancy and estrus-related deviations in the animal’s behavior. The result is noticeable almost immediately, from the first days of use. The pet stops screaming and rushing outside, becomes much calmer, and its aggressiveness decreases. The downside of the drug is its composition, which can ultimately provoke undesirable consequences. This is a deficiency of all hormonal agents used to regulate estrus in cats.

There are much more positive reviews about the drug than negative ones. Users appreciated the quick effect of use and availability, without noting strong side effects. For the most part, pets calm down, stop inviting cats, sleep more and eat well. So S.CONTROL, which combines an affordable price, quick effect and a minimum of side effects, is rightfully considered one of the best drugs in its category.

drops SexCONTROL

Advantages:

• low cost;
• quick effect;
• minimum side effects.

Flaws:

• not found.

SexBARRIER

A biohormonal drug, considered one of the best and most popular means for eliminating signs of sexual heat in cats. It acts quickly and effectively - it reduces aggression, has a sedative effect, and works as a contraceptive to prevent unwanted pregnancy and the birth of offspring. In the veterinary community, S. BARRIER is called one of the safest and most effective, especially in comparison with injections, even though the priority is the method of sterilizing animals rather than hormonal contraception.

The drug has earned a huge number of praises from grateful users, most of whom, having once tried its action, began to use it constantly. According to reviews from many cat owners, the drug very quickly calms their pets and removes aggression, thereby making life easier for both. The drug is available in the form of tablets or drops, separately for cats.

drops SexBARRIER

Advantages:

• highly effective;
• quickly reduces manifestations of aggressiveness;
• has a strong sedative effect.

Flaws:

• not found.

Pharmacological properties of the drug Depo-Provera

Medroxyprogesterone acetate (17-alpha-hydroxy-6-alpha-methylprogesterone acetate) belongs to gestagens (progestins) and is a derivative of progesterone. The drug does not have estrogenic activity, its androgenic activity is minimal. Depo-Provera in appropriate doses inhibits the secretion of pituitary gonadotropins, which in turn prevents the maturation of follicles, causing anovulation in women of childbearing age. When appropriate doses of the drug are used in men, the function of Leydig cells is inhibited (the formation of endogenous testosterone is inhibited). The antitumor effect of Depo-Provera in therapeutic doses in hormone-dependent malignancies may be associated with its effect on the hypothalamic-pituitary-gonadal axis, progestin and estrogen receptors, and steroid metabolism at the cellular level. Medroxyprogesterone acetate, like progesterone, has a pyrogenic effect. When used in very high doses, such as those used in the treatment of some types of cancer (500 mg/day and above), corticosteroid activity may occur. After intramuscular administration of medroxyprogesterone acetate, its release occurs slowly, which ensures the creation of low but constant concentrations of the drug in the blood plasma. The time to reach maximum concentration after intramuscular injection is approximately 4–20 days. However, medroxyprogesterone acetate is detected in the blood even 7–9 months after intramuscular administration. Almost 90–95% of medroxyprogesterone acetate is protein bound. The volume of distribution is 20±3 l. Medroxyprogesterone acetate crosses the blood-brain barrier and is excreted into breast milk. Currently, many metabolites of medroxyprogesterone acetate have been described. The half-life after intramuscular administration is 6 weeks. Medroxyprogesterone acetate is excreted mainly in bile and feces. Approximately 44% of the drug is excreted unchanged in the urine.

Check with your doctor

What questions should you discuss with your doctor if you are considering using Depo-Provera as a long-acting contraceptive?

• Change in body weight towards increase with long-term use of the drug
• Delay in the restoration of fertility - especially in light of the fact that there is no antidote for this remedy
• In the long term, the development of osteoporosis is possible, especially if the medicine was used uncontrolled and from adolescence (16-17 years)
• Duration of action of even a single dose (up to 12 weeks)
• Informing those wishing to use this particular contraceptive that monthly menstrual bleeding is not a mandatory attribute of a woman.
• It is possible that there will be frequent periodic acyclic mild bleeding.

Most often, women decide to use Depo-Provera for whom regular and daily use of oral contraceptives is inconvenient or even impossible due to employment or a busy business schedule. It is for this reason that they often miss the next injection - due to lack of time or forgetfulness.

But due to the residual hormonal effects of progestogens, a delay of up to 2 weeks with the next injection is not critical. And the longer the drug was used, the longer it is possible to miss the deadline (up to a month or more). So during this time, the woman will inevitably remember the next date for visiting the doctor’s office.

Mechanism of action of Depo-Provera

The mechanism of action is an increase in the viscosity of cervical mucus, a change in the condition of the endometrium and inhibition of ovulation stimulated by lutropin. The suppression of FSH secretion is not as significant as when taking oral contraceptives; the concentration of estrogen in the blood is comparable to that in the early follicular phase of the normal menstrual cycle. Manifestations of estrogen hormone deficiency, such as atrophic changes in the vaginal mucosa or a decrease in the size of the mammary glands, do not develop, but a decrease in bone tissue density is possible.

According to some researchers, cases of pregnancy that occur at the very beginning of using the drug are accompanied by an increased incidence of fetal or newborn death, presumably associated with an increased likelihood of intrauterine development disorders

Therefore, it is most important to take precautions in the period after the first injection of the drug. To ensure reliable contraception, the first injection should be carried out in the first 5 days of the cycle (before the dominant follicle ruptures) or additional contraception should be used for two weeks after the first injection. Failure to comply with the rules for using the drug reduces the duration of the contraceptive effect

The drug is injected into the muscle, changing the injection site (L-shaped); the place cannot be massaged. Injections should not be administered to areas subject to natural rubbing during movement.

Failure to comply with the rules for using the drug reduces the duration of the contraceptive effect. The drug is injected into the muscle, changing the injection site (L-shaped); the place cannot be massaged. Injections should not be administered to areas subject to natural rubbing during movement.

When is it time to think about it

Having reached 8, and sometimes 10 months of age, a cat begins to enter adulthood; simply put, its body is ready for reproduction and nothing can be done with the laws of nature. Around this time, the cat's first heat begins and a hormonal imbalance occurs in the body. From a small and fluffy ball, your pet turns into a wildly screaming cat. To be honest, such screams will lead the calmest person to a nervous breakdown.

shutterstock

Veterinarians often offer the option of sterilizing the animal, this partially solves the problem. But for various reasons, not all cat owners are ready for surgery. Contraindications for sterilization include:

• kidney diseases,
• heart disease,
• Anesthesia is contraindicated for the animal.

Just as not everyone is ready to have cat dates and wait for subsequent offspring, and if the cat does not have special advantages and pedigree, then another additional headache will arise - where to put the kittens.

Possible side effects

After taking hormonal drugs, male cats' desire for the opposite sex weakens or estrus stops (in cats). But, despite the high price, justified by the quality, there are often side effects:

1. Lethargy, depressed and apathetic state.
2. Excess weight, which is caused by increased appetite.
3. The likelihood of cancer or diabetes of any type.
4. Damage to, as well as disruption of the endocrine, as well as excretory and genitourinary systems.
5. The risk of developing mammary tumors in cats and other dangerous neoplasms.

Application in oncology

Depo-Provera is used:

1. As an additional or replacement treatment for recurrent forms of cancer and for metastatic oncology of the endometrium and kidney cancer.
2. As a palliative for hormone-dependent recurrent breast cancer in postmenopausal women.
3. At the last stages of all forms of oncology, when there are advanced tumors of various locations.
4. In men - with prostate carcinoma, as well as with certain forms of prostate adenoma.
5. The dosage of the medicine is determined by the attending physician strictly individually, based on the results of general and specialized blood tests. The treatment regimen is based on indications and stage of the disease.

Treatment of endometrial cancer and kidney cancer

The initial dosage for this type of oncology can range from 500 mg to 1 gram per week. If the condition improves, if it occurs within several weeks, a maintenance dosage of 500 mg per week is prescribed.

Breast cancer treatment

The initial dose of Depo-Provera for breast cancer is up to 500 mg per day for 28 days. Then maintenance injections of 500 grams are prescribed 2 times a week. Treatment continues until effectiveness is demonstrated or is stopped due to the futility of this method.

The effects of Depo-Provera on breast cancer may appear 9-10 weeks after the start of therapy, but if during it it turns out that the course is ineffective (which is quite possible due to a number of hormonal reasons), such treatment is immediately stopped.

Side effects during treatment with increased doses of the drug mirror the picture of contraindications when using the drug as a contraceptive. That is, if the list of contraindications includes thromboembolism as a blood clotting disease, then the use of large doses can cause this disease. The same applies to depression and nervousness in the central nervous system, and nausea in diseases of the gastrointestinal tract. And from the reproductive system, atypical discharge from the genitals, hypertrophied sensitivity of the mammary glands and galactorrhea are possible.

If high doses in the treatment of oncology have been used for quite a long time, symptomatic Itsenko-Cushing complex may occur. This is a whole complex of clinical symptoms characteristic of increased levels of corticosteroids in the blood, which causes a disorder of the hormonal system such as hypercortisolism.

The primary form of this syndrome is associated with pathological changes in the adrenal glands. And the secondary one can progress when the hypothalamic-pituitary system in the brain is affected. At the first manifestations of such symptoms, it is necessary to intensify monitoring of the patient and, if possible, reduce, sometimes significantly, the dosage of Depo-Provera.

Studying even the most thorough instructions for such a specific and multidisciplinary drug as Depo-Provera will not give anything to a patient or simply a patient who wants to receive a reliable method of contraception, without a thorough preliminary examination by a specialized doctor.

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How does Depo-Provera work?

This drug is controversial. And many faces. Using it in its pure form can contribute to the onset of a desired and long-awaited pregnancy. But combine it with the female hormone of the estrogen class, and you will receive a highly guaranteed contraceptive, which acts in this capacity, unlike other synthetic drugs, very gently: it inhibits the natural mechanisms of ovulation of the egg, and makes the mucus excessively viscous on the approaches to it. And in this mucus, the sperm get stuck, stuck, unable to move further, having reached the cervix - this last leg of the journey before the egg.

This same thickened mucus will prevent an ectopic pregnancy from occurring. Because the egg that was moving towards the sperm will also get stuck, not allowing it to merge with them “in an embrace.”

If a woman who decides to use Depo-Provera contraception does not have a phobia for intramuscular injections, and she has no contraindications to the use of this drug by the gynecologist observing her, then just one injection in the buttock will provide up to 12 weeks of contraception. And without compromising the contraceptive effect, the injection date can be moved a week earlier or later.

Mechanism of action

The mechanism of action is simple: a capsulated supply of the injected agent is formed in the injection, which begins to be slowly consumed, entering the bloodstream. Constant circulation in the circulatory system is possible because up to 95% of the administered drug is tightly bound to proteins, but is released as needed and takes on a free form.

The longer this drug is used as a contraceptive, the more time it takes for the body to completely eliminate it: after several years of use, traces of Depo-Provera disappear from the blood of patients only after 9-12 months after the last injection.

This method of contraception does not have any irreversible consequences. During its use, there is a significant decrease in the volume of menstrual flow, dysmenorrhea (pain in the lower abdomen during PMS and during menstruation) decreases, and PMS itself (premenstrual syndrome, characterized by increased irritability and even depressive states) weakens or even disappears.

The frequency of manifestations of endometriosis, that is, non-localized growths of internal cells of the uterus in places where they should not be by definition, is reduced: in places such as the bladder, rectum and even in the lungs. In this sense, endometriosis is similar in its course to an oncological disease, to metastases - but these formations are completely benign and do not pose a threat to health. Although they cause inconvenience because they are capable of bleeding inside any organs simultaneously with the onset of menstruation.

When to inject

If menstruation comes on time, without delays, then the optimal time for administering the drug is before the fifth day of the cycle. The drug begins to act immediately.

You can use it after childbirth, provided that 5-6 weeks have already passed since the birth of the child. Otherwise, the risk of spontaneous uterine bleeding increases.

If the injection is made within seven days after a miscarriage, moreover, without pathological consequences, or after an artificial termination of pregnancy, then the contraceptive effect also begins immediately, without any negative consequences.

Magic injection - Covinan and Depo-Provera

- Is it possible to give a cat such an injection, so that she doesn’t ask the cat? - from visiting a veterinary clinic

The question is simple, however, it has a global scale, is relevant for all times, all countries and peoples - where there are cats, there it exists.

And in order to answer it, you need to understand something, and understand it thoroughly.

Believe me, it's worth it.

Only the prince is missing, where did he go?..

Oh, these cat “wants”! More precisely, their lack of demand.

Starting from the age of 8-10 months (or even less!) In the cat’s head, the light bulb of the instinct “be fruitful and multiply!” begins to blink and send a signal, the same one that suppresses all other instincts and turns a cute creature into a small monster - heart-rendingly screaming , rolling around on the floor, leaving odorous marks. An instinct that makes the owner’s life similar to living on a volcano - it is not known when it will “explode”, which night will turn out to be sleepless.

To satisfy the sexual instinct, at least a sexual partner is required. Oops, but no one was going to give it to the cat. As well as creating conditions for the “getting to know each other” process. And the result of the meeting - kittens - is of no use to anyone... Let's not talk about how detrimentally this affects the cat itself - this is described in detail HERE. Let's talk about solving the problem.

What to do?

Of course, the most radical, most effective and healthiest thing in the whole wide world is CASTRATION-STERILIZATION. But the operation requires some effort from the owner, material and time costs and, finally, the desire to do it. It happens that something from this list is missing.

Then chemical melee weapons are used - Ex, Stop-intim, Sex-barrier, Counter-sex and other “contrasts” - pills or drops that interrupt estrus. Alas, they are all short-term or “it helped before, but now it doesn’t work.” Clearly something more efficient is required.

And then the owner comes to the idea that the pet needs a magic injection, about which a neighbor (friend, acquaintance or work colleague) told me: “you put it on, and that’s it!”

Long-acting hormonal contraceptives

There are several of them. But the two most popular are Covinan and Depo-Provera. We will consider them.

Covinan is a veterinary hormonal drug intended to suppress sexual estrus in bitches and cats. The active ingredient is prolygestone, a synthetic analogue of progesterone.

Prolygestone is a steroid hormone that prevents the development of estrus. It increases the viscosity of mucus in the uterus, which prevents the implantation of a fertilized egg, inhibits cell hyperplasia and secretion of the mammary gland. When administered during the phase of sexual rest (anestrus), prolygestone maintains a low concentration of LH - luteinizing hormone - in the cat's body, which provides contraception for the animal. When the drug is discontinued, the amount of prolygestone in the body decreases, normal LH levels are restored, and the contraceptive effect ceases.

How to do it correctly

To develop stable sexual dormancy in a cat, Covinan is used according to the following basic scheme:

INJECTION TIME INTERVAL

first injection during the period of sexual rest (anestrus)

second injection 3 months after the first injection

third injection 4 months after the second injection

subsequent injections 1 time every 5 months

This is how its manufacturer, the Netherlands, suggests putting Covinan. Its specialists conducted scientific research, taking into account the entire complex process of hormone production by the pituitary gland, hypothalamus and ovaries of the cat - all in order to make the drug the most effective and least safe. And this is important, because hormonal drugs are no joke. They also have a downside.

Side effects (from the instructions): When using the drug, in rare cases, pyometritis, endometrial hyperplasia, slight increase in body weight, increased appetite, apathy, and slight hypertrophy of the mammary glands are possible. Immediately after administration of the drug, a minor local painful reaction is possible. At the injection site, lightening of the coat and slight hair loss are possible.

The most common negative consequences are:

• pyometra (purulent inflammation of the uterus)
• breast tumors
• diseases of the endocrine system (diabetes mellitus)

Now let's look at the contraindications (from the instructions): Covinan is not used for pregnant or lactating animals; during estrus (estrus); animals with diseases of the genitourinary system; animals with prolonged vaginal discharge. For animals suffering from diabetes, the drug is used with careful monitoring of blood glucose levels.

Everything seems simple - injections are given according to a simple schedule during the period when there is no sexual heat. What do we have in reality?

Here's how it's usually done

As has been our custom since time immemorial, the system works “until the thunder strikes...”. While the cat is calm, its owner is also carefree. So she screamed obscenities, rolled on the floor, and began, God forbid, to shit in inappropriate places - and then the owner ran with her to the nearest hospital. He comes running and says: “Do something!”

And veterinarians are different - good and not so good. A good doctor, out of all the possibilities of “anything”, really wants to perform an operation - “the healthiest in the whole wide world.”

1. The doctor suggests sterilization first of all. But the owner believes that an injection is the best solution to the problem.
2. Then a good doctor talks about the possible consequences of such a hormonal injection. But the owner still believes that an injection is the best solution to the problem.
3. Then a good doctor examines the cat and, having detected signs of estrus, explains that it is a contraindication to the administration of the drug and talks about the correct regimen. But the owner still insists on the injection.
4. Then a good doctor gives this injection. Why? Yes, because in case of refusal, the stubborn owner will go to another clinic, where there may not be a very good doctor.

A not very good doctor will give the injection right away.

Depo-Provera Unlike veterinary Covinan, Depo-Provera is a medical drug, one of the first synthetic progesterone hormones, developed to prevent conception in women (as well as as a treatment for certain gynecological and oncological diseases). The active ingredient is medroxyprogesterone. It comes in the form of a suspension or tablets.

Due to its ability to suppress ovulation, Depo-Provera is used as a long-acting contraceptive.

The drug has restrictions on use and a wide range of side effects, including reactions from various organs (in women). For cats, estrus is still a contraindication. The same negative consequences are also possible.

Depo-Provera is preferred by veterinarians at clubs and nurseries, and breeders of purebred cats.

Who can and needs it?

It is advisable to use hormonal drugs to interrupt estrus in breeding animals, cats that have contraindications to anesthesia and surgery in general (for example, with heart disease, kidney disease, etc.). Contraceptives are also given to cats whose estrus unexpectedly resumes after castration.

Cats in breeding

Perhaps, this category of animals really needs long-acting contraceptives. The mating and resting schedule between them implies the presence of empty heats, and hormonal drugs such as Covinan or Depo-Provera (or its analogues) help to survive them with the least damage.

Here's how a veterinarian who works with cat nurseries talks about it (watched on the forum of the Vetmedical portal): If the animal is a breeding animal, used for breeding, but has violent, debilitating estrus, the use of hormones in adequate doses and at adequate times is justified. True, such cats are not removed from breeding at an advanced age. Well, there are no options for the operating table.

So what happens as a result of the injection?:

The administration of the drug stops the development of estrus in the cat and removes all its negative manifestations. And everyone will be happy!

Or the cat still ends up on the operating table, only under much worse circumstances. Or treatment of the endocrine system will be required.

Are there always negative consequences after using hormonal contraceptives?

No. This is roulette.

Some cats “sit” on pills and injections all their lives, and no matter what (at least it seems so, since there are no visible changes).

For others, it “shoots” right away. Or after some time (perhaps after a year). If we get lucky.

Gag: Do you know how many owners come to the clinic demanding that their cat be given a hormonal injection? - A lot of. Do you know how many of them do it the way it should be done? - Units. Almost all injections are given “when the need arises,” that is, during sexual heat.

Dear cat owners! If you do not plan to have kittens, sterilize your pet right away. This will make life a lot easier for both him and you. But if you have already decided to fight the reproductive instinct with the help of hormones, then please do it correctly! After all, there is no one else to take care of your cat except you.

PS Is it possible to give a cat such an injection, so that she doesn’t ask the cat? - from visiting a veterinary clinic

Yes, you can. But first of all, be careful. Secondly, is it necessary?

Features of an estrus injection for cats

When a pet is ready to reproduce, the process of estrus begins in her body, scientifically called estrus. Animals often begin to roll on the floor, meow pitifully or scream heart-rendingly. This period occurs approximately twice a year in mature cats. Even if you plan to breed kittens, giving birth too often is unhealthy for your cat, which means you need to somehow help her survive this period.

A popular method is injection; it is fraught with several difficulties. Contrary to popular belief, this is not a one-time panacea for the unpleasant symptoms of estrus. The doctor must give injections at a certain frequency; for this purpose, a specific drug administration regimen is even developed. In addition, there are certain contraindications to the administration of hormonal drugs. Therefore, under no circumstances should you give the first injection yourself.

After a thorough examination, the veterinarian injects the cat with a special drug that changes the level of hormones in the animal’s body. The most commonly used are Covinan or Depo-Provera. Both substances contain a synthetic hormone that temporarily increases progesterone levels. The administration of the drug interferes with the ovulation process, as the hormonal background changes slightly. As a result, the pet does not suffer from the desire for intimacy with the cat, and the owners are no longer forced to listen to the animal’s endless cries.

As we have already said, the drug is administered according to a certain scheme. A prerequisite is that the injection is done during the rest period; in no case should the procedure be done if the cats are in heat. The second injection is given three months after the first injection, the third after four months, and each subsequent injection at intervals of five months. This periodicity is based on deep scientific research, so it should not be neglected.

How the cat feels after the injection

To ensure that the injection does not affect your pet’s well-being, contact a competent veterinarian. He will examine the animal and select the correct drug and dosage. Then the risk of complications after the injection will be minimized. And yet, it is there, which means the animal is in danger. Therefore, think carefully before you decide to use such methods of contraception.

Contraindications and complications

The use of Covinan can be successful for some cats, but for others it can lead to the following diseases:

• purulent inflammation of the uterus;
• mammary cancer;
• diabetes.

If your cat's doctor has discovered problems with the genitourinary or endocrine system, hormonal injections are contraindicated. Do not use the drug if the cat is carrying cubs or feeding them milk. Wait until the kittens are mature and the cat goes through her lactation period.

Most veterinarians advocate that the best method of contraception for cats with minimal health risks is neutering. If you breed kittens and the reproductive function of your pet is important to you, then a hormonal injection will help you avoid unpleasant symptoms during periods when you do not plan to mate your pet.

The most important requirement for such an injection is that the pet must be healthy and in a state of sexual rest. And although there are irresponsible veterinarians who, at the client’s request, will give an injection to an animal in any condition, be responsible owners

After all, who will protect your pet if not you. If the injection will only benefit the cat, and the health risks are minimal, then all that’s left is to find a good clinic and a reliable specialist.

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Hormonal Injection for Cats - What You Need to Know:

- Is it possible to give a cat such an injection, so that she doesn’t ask the cat? — from an appeal to a veterinary clinic
The question is simple, nevertheless, it has a global scale, is relevant for all times, all countries and peoples - where there are cats, there it exists.

And in order to answer it, you need to understand something, and understand it thoroughly.

Believe me, it's worth it.

Only the prince is missing, where did he go?..

Oh, these cat “wants”! More precisely, their lack of demand.

Starting from the age of 8-10 months (or even less!) In the cat’s head, the light bulb of the instinct “be fruitful and multiply!” begins to blink and send a signal, the same one that suppresses all other instincts and turns a cute creature into a small monster - heart-rendingly screaming , rolling around on the floor, leaving odorous marks. An instinct that makes the owner’s life similar to living on a volcano - it is not known when it will “explode”, which night will turn out to be sleepless.

To satisfy the sexual instinct, at least a sexual partner is required. Oops, but no one was going to give it to the cat. As well as creating conditions for the “getting to know each other” process. And the result of the meeting - kittens - is of no use to anyone... Let's not talk about how detrimentally this affects the cat itself - this is described in detail here. Let's talk about solving the problem.

What to do?

Of course, the most radical, most effective and healthiest thing in the whole wide world is CASTRATION-STERILIZATION. But the operation requires some effort from the owner, material and time costs and, finally, the desire to do it. It happens that something from this list is missing.

Then chemical melee weapons are used - Ex, Stop-intim, Sex-barrier, Counter-sex and other “contrasts” - pills or drops that interrupt estrus. Alas, they are all short-term or “it helped before, but now it doesn’t work.” Clearly something more efficient is required.

And then the owner comes to the idea that the pet needs a magic injection, about which a neighbor (friend, acquaintance or work colleague) told me: “you put it on, and that’s it!”

Long-acting hormonal contraceptives

There are several of them.
But the two most popular are Covinan and Depo-Provera. We will consider them. Covinan is a veterinary hormonal drug intended to suppress sexual estrus in bitches and cats.
The active ingredient is prolygestone, a synthetic analogue of progesterone. Prolygestone is a steroid hormone that prevents the development of estrus. It increases the viscosity of mucus in the uterus, which prevents the implantation of a fertilized egg, inhibits cell hyperplasia and secretion of the mammary gland. When administered during the phase of sexual rest (anestrus), prolygestone maintains a low concentration of LH - luteinizing hormone - in the cat's body, which provides contraception for the animal. When the drug is discontinued, the amount of prolygestone in the body decreases, normal LH levels are restored, and the contraceptive effect ceases.

How to do it correctly

To develop stable sexual dormancy in a cat, Covinan is used according to the following basic scheme:

This is how its manufacturer, the Netherlands, suggests putting Covinan. Its specialists conducted scientific research, taking into account the entire complex process of hormone production by the pituitary gland, hypothalamus and ovaries of the cat - all in order to make the drug the most effective and least safe. And this is important, because hormonal drugs are no joke. They also have a downside.

Side effects (from the instructions): When using the drug, in rare cases, pyometritis, endometrial hyperplasia, slight increase in body weight, increased appetite, apathy, and slight hypertrophy of the mammary glands are possible. Immediately after administration of the drug, a minor local painful reaction is possible. At the injection site, lightening of the coat and slight hair loss are possible.

The most common negative consequences are:

• pyometra (purulent inflammation of the uterus)
• breast tumors
• diseases of the endocrine system (diabetes mellitus)

Now let's look at the contraindications (from the instructions): Covinan is not used for pregnant or lactating animals; during estrus (estrus); animals with diseases of the genitourinary system; animals with prolonged vaginal discharge. For animals suffering from diabetes, the drug is used with careful monitoring of blood glucose levels.

Everything seems simple - injections are given according to a simple schedule during the period when there is no sexual heat. What do we have in reality?

Here's how it's usually done

As has been our custom since time immemorial, the system works “until the thunder strikes...”. While the cat is calm, its owner is also carefree. So she screamed obscenities, rolled on the floor, and began, God forbid, to shit in inappropriate places - and then the owner ran with her to the nearest hospital. He comes running and says: “Do something!”

And veterinarians are different - good and not so good (see here). A good doctor, out of all the possibilities of “anything”, really wants to perform an operation - “the healthiest in the whole wide world.”

1. The doctor suggests sterilization first of all. But the owner believes that an injection is the best solution to the problem.
2. Then a good doctor talks about the possible consequences of such a hormonal injection. But the owner still believes that an injection is the best solution to the problem.
3. Then a good doctor examines the cat and, having detected signs of estrus, explains that it is a contraindication to the administration of the drug and talks about the correct regimen. But the owner still insists on the injection.
4. Then a good doctor gives this injection. Why? Yes, because in case of refusal, the stubborn owner will go to another clinic, where there may not be a very good doctor.

A not very good doctor will give the injection right away.

Depo-Provera Unlike veterinary Covinan, Depo-Provera is a medical drug, one of the first synthetic progesterone hormones, developed to prevent conception in women (and also as a treatment for certain gynecological and oncological diseases). The active ingredient is medroxyprogesterone. It comes in the form of a suspension or tablets.

Due to its ability to suppress ovulation, Depo-Provera is used as a long-acting contraceptive.

The drug has restrictions on use and a wide range of side effects, including reactions from various organs (in women). For cats, estrus is still a contraindication. The same negative consequences are also possible.

Depo-Provera is preferred by veterinarians at clubs and nurseries, and breeders of purebred cats.

Who can and needs it?

It is advisable to use hormonal drugs to interrupt estrus in breeding animals, cats that have contraindications to anesthesia and surgery in general (for example, with heart disease, kidney disease, etc.). Contraceptives are also given to cats whose estrus unexpectedly resumes after castration (more on this here).

Cats in breeding

Perhaps, this category of animals really needs long-acting contraceptives. The mating and resting schedule between them implies the presence of empty heats, and hormonal drugs such as Covinan or Depo-Provera (or its analogues) help to survive them with the least damage.

Here's how a veterinarian who works with cat nurseries talks about it (watched on the forum of the Vetmedical portal): If the animal is a breeding animal, used for breeding, but has violent, debilitating estrus, the use of hormones in adequate doses and at adequate times is justified. True, such cats are not removed from breeding at an advanced age. Well, there are no options for the operating table.

So, what happens as a result of the injection:

The administration of the drug stops the development of estrus in the cat and removes all its negative manifestations. And everyone will be happy!

Or the cat still ends up on the operating table, only under much worse circumstances. Or treatment of the endocrine system will be required.

Are there always negative consequences after using hormonal contraceptives?

No. This is roulette.

Some cats “sit” on pills and injections all their lives, and no matter what (at least it seems so, since there are no visible changes).

For others, it “shoots” right away. Or after some time (perhaps after a year). If we get lucky.

Gag: Do you know how many owners come to the clinic demanding that their cat be given a hormonal injection? - A lot of. Do you know how many of them do it the way it should be done? - Units. Almost all injections are given “when the need arises,” that is, during sexual heat.

Dear cat owners! If you do not plan to have kittens, sterilize your pet right away. This will make life a lot easier for both him and you. But if you have already decided to fight the reproductive instinct with the help of hormones, then please do it correctly! After all, there is no one else to take care of your cat except you.

PS Is it possible to give a cat such an injection, so that she doesn’t ask the cat? - from visiting a veterinary clinic

Yes, you can. But first of all, be careful. Secondly, is it necessary?

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Preparing for the injection

To administer medicine by puncturing and inserting through play into the selected type of tissue, you must first prepare for this manipulation. You will need a syringe and the drug itself for administration. Cotton wool and alcohol are not required for wiping; cats have an antibacterial layer on their skin, which allows them not to lubricate the injection site.

General safety rules

Injection is a medical intervention that violates the integrity of tissues. To ensure that it is as safe as possible, promotes treatment and does not cause complications, do not neglect preparation. Here's what you need to take into account to take care of the health of a cat that is about to get an injection.

Do not give injections unless prescribed by a doctor. Self-medication or incompetent recommendations can cause serious harm.

Before starting the procedure, wash your hands thoroughly. Even with clean fingers, you should not touch the syringe needle after the protective cap has been removed.

Give injections only in the place indicated by the veterinarian

For most drugs this is fundamentally important. Follow the dosage exactly.

Do not use expired medications or ampoules with worn-out markings. Always check the name of the drug before dialing. You cannot take a second dose of the drug from an opened ampoule over time.

Prepare all the items needed for the injection in advance. So that they are at hand: an ampoule or bottle of medicine, a syringe.

Usually cats feel and “mirror” the state of the owner, so most of them endure painful procedures and, feeling cared for, even express their feline gratitude for them. In such situations, it is advisable to give the injection alone. But in some cases it is better to ask a partner to help - to hold the sufferer more tightly:

• you are not completely confident in yourself;
• a cat with a temperament, prone to scratching and biting;
• the animal is not yours or was recently taken into the home and is not sufficiently tamed.

In extreme cases, you can swaddle the animal in a blanket or towel, exposing only the injection site.

Study of the drug

The main rule is that you should never prescribe for your cat yourself. “But it helped our cat”, “An excellent product”, “Even a child was injected” - all these are not arguments, since in each specific case there may be serious nuances, ranging from the tolerability of the drug by your cat and ending with the individual dose. Only two drugs can be safely injected before consulting a doctor: saline solution and 10% glucose solution. This may be necessary if the cat is dehydrated and malnourished. For one injection to a medium-sized cat, 10 ml is enough; an overdose of these drugs is not dangerous.

If your doctor makes an appointment, stick to it exactly. Do not mix medications in the same syringe unless directed by your veterinarian. Before injection, make sure that the medicine is not expired, check the name again. If it was stored in the refrigerator, take it out in advance or warm it a little in your hand.

Choosing a syringe and injection site

There is no doubt that syringes and needles can only be used once. Human syringes from any pharmacy are suitable for cat injections. It is better to prefer the thinnest possible needles and not a tight piston. If you are going to draw the drug through a rubber stopper, you will need an additional needle, because when the rubber is punctured, it becomes dull. There are syringes sold with two needles in a set, or take it from another package.

If you need to inject no more than 1 cc (1 ml), it is better to take an insulin syringe with a short and very sharp needle; for a larger volume, you will need a regular 2-5 cc syringe; for glucose or saline, a 10 cc syringe. If it is possible to switch a smaller needle to a larger syringe, it is worth doing so.

Where to inject

If a subcutaneous injection is prescribed, the easiest way is to give an injection at the withers. This place is the least sensitive in cats: the mother cat carries the kitten, holding it in her teeth, and adult cats also grab each other there during a fight. In addition to the withers, subcutaneous injections can be given:

• between the shoulder blades;
• into the knee crease.

Intramuscular manipulations are performed in the thigh (in the back surface), it is also possible to do this in the shoulder (in the front leg on the side). The meatiest part is selected.

The most important thing is that the skin at the injection site is healthy and not damaged.

Please contact your operator for the cost of services not listed in the price list.

Steps

Part 1

Preparing for Depot Injection

1. 1

   Visit your doctor to get a prescription for Depo-Provera.

   To receive a prescription for an injection, you must undergo a complete gynecological examination in advance.

   Your doctor will discuss different birth control options. You may need to purchase the Depot injection from a pharmacy yourself; your doctor should give you the first few injections.

2. 2

   Buy a pregnancy test.

   Most doctors will require a test if more than 14 weeks have passed since the first injection. It is not recommended to use Depo injections if you want to become pregnant by next year, as the process of conception may be problematic in the period from 10 months to one year.

3. 3

   Review your medical history.

   In addition to the injection being difficult for people with allergies, this form of birth control is also not recommended if the person suffers from blood clots, swollen veins, cancer, blood pressure problems, asthma, migraines, epilepsy, diabetes, bone disease, eating disorders or depression.

4. 4

   Arrange for a Depo injection during the first five days of your period.

   This is a necessity when receiving your first injection. If you have just given birth, you must wait 6 weeks after your baby is born before getting the injection.

5. 5

   Ask to be given permission to administer the injection yourself at home.

   After a long course of injections, to save time and money, your doctor may allow you to administer the injections yourself at home.

Part 2

Injection Injection

1. 1

   Get your dose of Depo-Provera.

   To use as a contraceptive, you will need 150 mg every three months. You will likely need more than 1000 mg each week if used as a cancer treatment.

2. 2

   Remove the 1 ml disposable syringe from the container.

   The liquid appears white and cloudy.

3. 3

   Wash your hands.

4. 4

   Decide whether you will inject the injection intramuscularly in the shoulder or buttock.

   An injection into the buttock is considered less painful and easier to give than an injection into the shoulder. If you inject yourself, use a mirror.

   • Find the upper right or left muscle if you are planning to inject into the buttock. If you divide the muscle into four sectors, you will have to insert it into the upper outer sector to avoid hitting the nerve. This is the fattest or most muscular area below the thigh, so feeling this fleshy area with your hand will ensure that you have located the right spot.

   Find the injection site on your upper arm. Find the edge of the shoulder where it slopes down smoothly. Use two fingers to select the injection point—one to two inches (2.5 to 5 cm) below the bony area of ​​the shoulder. The area should be a little meaty and a little towards the back of your hand rather than the front.

5. 5

   Disinfect the indicated areas with a swab soaked in alcohol.

   Wait a few seconds for the area to dry.

6. 6

   Apply gentle pressure to the syringe to release any air bubbles.

   Then press the handle of the syringe until a small amount of liquid approaches the needle so that there is no air left in the syringe.

7. 7

   Pull the skin tightly over the area where you want to inject.

   Insert the needle directly into the skin at a 90-degree angle. Insert the needle only halfway.

8. 8

   Pull the syringe handle all the way until you have injected all the liquid.

   Pull the needle out quickly.

9. 9

   Cover the injection site with a sterile cotton swab for 30 seconds.

   Apply light pressure to the injection site. If the injection area bleeds, use a bandage, although this is rare.

Part 3

Storage of Depo-Provera

1

Pay attention to the expiration date on syringes containing Depo-Provera. If the dose has expired, return the dose to your pharmacy.

2

Do not store Depo-Provera doses in the bathroom or near the sink.

Humidity may reduce the effectiveness of the dose.

3

Store Depo-Provera doses in a cool place, below 77 degrees Fahrenheit (25 degrees Celsius).

Flaws

Birth control has disadvantages

Depo-Provera is no different, and it's important to know both the pros and cons before making your decision

Planning is important and you must remember that you plan to take injections every 12 weeks. If it has been more than 13 weeks since your last shot (or 14 weeks since your last Depo-subQ 104), be sure to use a back-up birth control method because you are at risk of becoming pregnant. The instructions for Depo-Provera contain a warning about possible bone loss: “Women who use Depo-Provera may lose significant bone mineral density.”

This measure measures how much calcium is stored in the bones. Depot use can cause calcium loss over time, but calcium begins to return once this method is stopped. Because of this warning, Depo-Provera is generally not recommended for teenage girls. Due to the possibility of bone density loss, it is also recommended not to use Depo Provera or Depo-subQ Provera 104 for more than two years. Many women stop using Depo-Provera within the first year of use due to spotting/irregular bleeding and/or continuous bleeding. This side effect is especially common during the first 3 months of using Depo. Unfortunately, there is no way to know in advance whether you will experience these bleeding problems. In a small number of cases, women experienced skin reactions in the area where the injection was given. There may also be a dimple or lump around the injection. Pfizer, the maker of Depo-Provera, recommends that you stop taking Depo injections a year before you want to become pregnant. It takes an average of nine to ten months (and sometimes a year or longer) to restore fertility and begin ovulation after the last shot. Some studies have shown weight gain with Depo-Provera. The manufacturer claims that women gain an average of 3kg in the first year and will gain 3.6kg by the end of the second year. Some women report mild pain associated with the Depo injection. Unfortunately, there is no way to stop the side effects that may occur from using Depo-Provera. There is a chance that these side effects may continue until your depot injection wears off after 12 to 14 weeks.

Fewer common side effects

During the first year of Depo, you may notice several changes as your body adjusts. Additionally, some of the less common side effects include changes in sex drive and appetite, as well as hair loss and/or increase in facial or body hair. In a few women, it may cause depression, nervousness, dizziness, nausea or headaches. You may also experience a rash or patchy darkening of the skin or chest pain.

Additional Considerations

• If you are using another hormonal method, you may want to switch to Depo-Provera. You must get your first Depo shot within seven days of the last day of your current method.
• If you are switching from combined birth control pills, arrange for your first Depo shot within seven days of taking your last active pill.
• If you switch from the Ortho Evra patch, schedule a Depo-Provera injection for seven days after removing the patch.
• If you switch from NuvaRing, schedule your first Depo shot within seven days after you remove the ring.

Symptoms of estrus in a cat and ways to suppress it

The first time a cat goes into heat occurs in the age category from 7 to 9 months. Final puberty occurs between one and one and a half years. The period of estrus occurs in stages and is determined by symptoms:

• slight swelling of the genitals;
• frequent urination;
• increased hygiene procedures, accompanied by licking of the pelvic area;
• lack of need for food;
• demand for attention and affection - the animal rubs, twists on its back and loudly emits inviting cries (sometimes day and night);
• attempts are made to jump out of the apartment in any available way (through the door or out the window);
• the pet bends its lower back, retracts its tail, bends its hind legs, and takes poses characteristic of mating.

The cat has a strong desire to go for a walk, and this behavior causes trouble for its owner, worsening the quality of life. Estrus lasts about 10 days. If during this time she has not mated with a male, or measures have not been taken to suppress sexual activity, after 14 days the estrus may recur.

Types of Anti-Party Remedies for Cats

Relief of symptoms and complete disappearance of signs of estrus is possible with the help of various remedies for cats from walking. They are hormonal (chemically based), sold separately for females and males (to suppress sexual heat) and herbal, containing herbal components.

1. Hormonal drugs. Contains chemicals. To date, there are no safe hormonal treatments for animals. Their long-term use to suppress estrus increases the risk of complications associated with the endocrine system, as well as oncology.
2. Vegetable (herbal based). They have a slight sedative effect due to their cumulative effect, so they need to be used for a long time. They have a relatively harmless effect, but do not bring immediate calm.

Important! It should be remembered that contraceptives for cats are a medicine prescribed by a veterinarian as a means to urgently stop estrus or temporarily suspend it. It is not recommended to give it at the onset of the first heat.

Drops

Walking drops for cats are a light yellow oily liquid. Before taking, they should be shaken thoroughly to break up sediment. Antisex drops for cats containing synthetic progestogen suppress libido. May contain both natural and chemical components. Using a pipette, they are placed on the root of the tongue or introduced into the body with a small amount of food before feeding 1-2 hours.

Advantages of the product:

• regulates the sexual behavior of cats and the associated manifestation of aggression;
• stabilize the sexual cycle;
• rapid action of the drug.

Antistress drops are an additional drug prescribed in conjunction with contraceptives to correct psychogenic disorders in cats.

When the recommended dosages are administered, there are no adverse reactions; with long-term use of drops for cats from walking, the following phenomena may occur:

• increased appetite and weight;
• suppression of adrenal cortex function and atrophy;
• behavior change.

Important! Violation of the administration system specified in the instructions for use may lead to a decrease in the therapeutic effect.

Pills

Tablets for cats against partying are given to animals strictly according to the scheme, and not at the request of the owner. Oral contraceptives should be taken no later than 3 days from the start of sexual heat, and the best option is on the first day. The drug is used one tablet for 6-8 days, but according to different schemes. A prerequisite for the effectiveness of the intake is compliance with the frequency of taking pills to stop estrus - no more than twice a year.

The advantages of taking pills are:

1. Nonestron reduces sexual activity, calms and discourages the desire to mark territory. When taken correctly, it has a contraceptive effect if mating occurs.
2. Contrasex suppresses sexual arousal in cats, removing them from a state of aggression during the period of manifestation of the procreation instinct. Has an anti-stress effect.

Anti-festival tablets for cats are quickly absorbed and show high effectiveness in suppressing sexual heat. They are eliminated from the body within 15 days.

Disadvantages of taking pills for cats:

• enlargement of the mammary glands;
• profuse drooling;
• lead to serious hormonal imbalances, for example to purulent inflammation of the uterus;
• Gynecological disturbances in the functioning of organs may occur, leading to neoplasms on the uterus.

Important! It should be remembered that when using any hormonal drugs there is a high risk of complications. Therefore, you should not once again expose your furry pet to danger; it is better to take care of it.

Injections

Almost every veterinary clinic offers hormonal injections. The first time a cat is given an injection from a walk, a doctor must give it, and then you can carry out the procedure yourself, injecting the drug subcutaneously into the fold on the withers, treating the injection site with alcohol. The injection is given a few days before the expected heat using sterile gloves. If necessary, you may need the help of a household member holding the pet. A single dose is calculated based on the weight of the animal.

Chemical sterilization has advantages:

• helps to stop estrus with the removal of negative consequences, maintaining the effect for 4-6 months after a single use;
• can be carried out at home under the supervision of a veterinarian or subject to strict adherence to the recommendations received from him;
• over time, the body’s reproductive capacity is restored; after time, the cat can become pregnant, bear and give birth to healthy offspring;
• onset of rapid positive impact.

With the help of injections, the behavior of a pet is corrected so that the cat does not wander, and the owner finds peace in his own home.

Still, veterinarians do not really approve of this method, highlighting the following disadvantages:

• hormonal injections can subsequently cause various cancers;
• lead to side effects (the appearance of cysts and purulent rashes in animals);
• a long course (from two years) causes aggression, increased appetite, and excess weight in cats;
• The injections are very painful - after the injection the animal recovers for several days.

On a note! The cost of resolving the issue is low; on average, an injection costs about 200 rubles.