Globfel-4 drug for immunization of cats, instructions, indications

What will you learn from the article?

Instructions for use Globfel-4 for cats
Dosage
Advantages and disadvantages Contraindications
Side effects

Reviews of the drug Globfel for cats

Prices

Do you know when your cat might need an immunomodulator? Those who believe that such a drug will only work if the animal is sick are wrong.

The medicine that you will read about in this material actively works both against major cat infections and as a preventative.

And all because Globfel-4 for cats contains globulin gamma and beta particles from the blood of oxen, horses, and goats. Consequently, the drug carries antigens of specific feline viruses. Which ones? More on this later!

Composition and release forms

The active substances that make up the drug Globfel-4 are beta and gamma globulins from the blood of some animals (goats, horses or oxen) with antibodies to calicivirus, infectious rhinotracheitis (or feline herpes), panleukopenia (or feline distemper) and chlamydia . Available in 1 ml bottles (1 dose), in the form of liquid for injection. Externally, the product looks like a transparent or odorless opalescent solution, the color of which varies from transparent to pale yellow. There may be a small amount of sediment at the bottom of the bottle, which dissolves very quickly when shaken.

Contraindications and side effects

A contraindication to the use of the drug is the weakening and exhaustion of the animal caused by a disease other than those for which Globfel-4 is used.

When used correctly in accordance with the instructions, there are practically no side effects when taking the drug. There may be slight pain during the administration of the medicine, as well as allergic reactions. To prevent the latter, it is recommended to give your pet an antihistamine before injecting the next dose.

Special instructions and precautions

The drug can only be used if the following precautions are followed:

The medicine should not be allowed to come into contact with the skin; therefore, procedures involving its use should be carried out wearing medical gloves, masks, a gown and trousers. If Globfel-4 gets on the skin, then it is necessary to rinse the area with plenty of water. The same applies to mucous membranes.
If the drug was accidentally administered to a person, it is necessary to contact a medical facility as soon as possible. As first aid, the injection site should be treated with a 70% ethanol solution.

Indications for use

Globfel is widely used in veterinary medicine for preventive vaccination and treatment of:

panleukopenia (feline distemper); calcivirosis; acute respiratory rhinotracheitis; chlamydia.

Panleukopenia, or more commonly known as feline distemper, affects the nasopharynx and gastrointestinal tract of felines. The risk of infection for a pet is very high, since literally the owner’s shoes serve as a carrier of the disease. A timely injection of Globfel-4 serum stops the infection.

Calicivirus infection, or feline calicivirus, affects the upper respiratory tract against the background of a febrile syndrome and the formation of ulcers in the mouth and on the tip of the nose. Treatment of calcivirosis with Globfel is carried out as part of complex antiviral therapy.

Acute respiratory rhinotracheitis is also called feline herpes. Its danger lies in the fact that even cats that have recovered from the disease remain carriers of the disease for about 9 months. Infection occurs through any, even indirect, contact with a cat carrying the virus. The disease affects the eyes and respiratory organs. Ideally, it is necessary to carry out preventive vaccination, but even if your pet is sick, Globfel therapy brings good results, especially in the initial stages of the disease.

Chlamydia is a disease caused by chlamydia entering the body. Foci of damage are the respiratory organs, eyes, gastrointestinal tract and genitourinary system. The use of serum helps to alleviate the symptoms of the disease and also rids the body of its pathogens.

Advantages

Globfel-4 is an innovative drug used for preventive measures and the fight against dangerous infectious diseases in cats. The main advantages of the drug are:

Wide range of effects;
Increased efficiency;
possibility of use as part of complex therapies;
cannot cause symptoms of illness if dosages are exceeded;
no side effect;
Use for cats of any age;
there is no additional component, that is, the toxin cannot accumulate in the body;
short course of use.

Globfel-4 is a serum against viral infections in cats and kittens.

Instructions for use

The drug is administered subcutaneously. To avoid anaphylactic reactions to immunoglobulins, an antihistamine should be given to the sick pet 10–15 minutes before the injection.

To prevent infectious and viral diseases and strengthen the immune system, the serum is used once in the following dosage: for animals whose weight does not exceed 10 kg, the drug is administered subcutaneously in a volume of 1 dose (1 ml); if the cat's weight exceeds 10 kg, the dose is doubled (2 ml).

When using Globfel for medicinal purposes, the dosage remains the same. A total of 2 to 4 injections are given, keeping an interval between them from 12 hours to 1 day.

The maximum effect is observed when taking Globfel in the initial phase of the disease. It is recommended to carry out therapy with Globfel-4 together with symptomatic treatment, in combination with antibacterial and vitamin preparations, as well as probiotics.

Before preventive vaccination, it is recommended to carry out antiparasitic and anthelmintic therapy.

Prophylaxis with Globfel-4 should not be carried out on a weakened animal.

The drug must be stored in a dry, dark place at a temperature of 2 – 8 C. Immediately before use, warm to room temperature.

Precautionary measures

It is forbidden to use Globfel-4 after the expiration date, if the packaging is damaged, the color of the substance has changed, or a large amount of sediment has formed. The product must not be frozen. When working with the drug, you should strictly follow the rules of personal hygiene and safety precautions: use only disposable syringes and gloves, do not allow the substance to come into contact with the skin, wear special clothing.

Limitations in use

The drug should not be mixed in a syringe with other medications. Before use, you should consult a veterinarian. If a specialist has questions about the cat’s condition, he may order additional tests before Globfel-4 vaccination.

Possible side effects

If the recommendations, doses and instructions were followed, no dangerous side effects were found. To exclude the possibility of an allergic reaction, antihistamines are administered. The most common options are Fexofenadine, Cetirizine, Hydroxyzine.

When treating diseases, antibiotics, probiotics and vitamins are prescribed together with Globfel-4. Under no circumstances should you mix medications into one injection.

Reviews

Inessa:

When my cat suddenly started sneezing, I admit, I didn’t pay much attention to it. But the next day her eyes began to water and she developed a runny nose. At this point I sounded the alarm and took her to the vet. My kitty was diagnosed with rhinotracheitis. The doctor prescribed a comprehensive treatment for us with Globfel. We injected it for 4 days, with a 12-hour break between injections. I had to give the injections myself, so as not to torment the poor animal with trips on public transport. After the first injection, the cat felt noticeably better, and a week later, during a follow-up examination, the veterinarian confirmed that we had recovered.

Arina:

We picked up a small kitten on the street. We decided to keep him and, of course, the next day we took him to the veterinary clinic. In addition to treatment for worms and fleas, the veterinarian strongly recommended piercing Globfel-4 for 10 - 15 days, since the animal spent a long time on the street and could pick up anything. The injection schedules were outlined for us. They injected the drug on their own, before the injection they gave the cat a crushed tablet of suprastin to avoid anaphylactic shock. Everything went well, the cat is healthy, and there were no side effects from using Globfel.

Magda:

The kitten was prescribed this drug, but after the injections his breathing quickens and he becomes drowsy. This is fine?

Fedor:

We took our Frosya to the veterinary hospital after she had been sneezing and “sniffling” non-stop for 24 hours. The specialist who examined her said that the cat was infected with feline herpes, or rhinotracheitis. Prescribed by Globfel. After 4 days, Frosya should have been brought in for an examination. My wife, a nurse by profession, did the injections. There were a lot of problems with the injections, but it was worth it. A week later the cat recovered. We believe that the medicine helped.

Stanislav:

We found a small kitten in the entrance. We consulted with a veterinarian we know, who advised us to give him a one-time injection of Globfel. We were all very scared when, after the injection, the baby began to vomit severely and then have diarrhea. It turned out that before vaccination it was necessary to give the cat some kind of antihistamine. It's good that everything worked out!

Self-injections of Globfel to a cat

Since the drug is used through injections that are injected into the animal’s body, you should carefully study the question of where to inject Globfel into a cat. It is worth noting that for greater effectiveness of the drug, your pet should be prepared.

There are certain preparation rules:

A week before using the drug, it is worth carrying out procedures aimed at preventing parasites and worms.
It is necessary to make sure that the pet is not sick with any diseases, since Globfel is more aimed at a preventive effect.
Before the injection, the cat should be calm, just like its owner. After all, in a restless state it will be much more difficult to give an injection.

It should be understood that using this drug without carefully studying how to administer Globfel to a cat is dangerous. Before using this drug, you should study the instructions for use and consult a veterinarian.

Let's look at some features of the injection:

It is recommended to administer the medicine with a disposable syringe and needle.
The drug is administered into the cat's body by injecting it into the femur or under the withers of the pet.
It is necessary to carefully observe the dosage of the drug, which may vary depending on the weight of the animal.
The drug is administered only once a day for preventive measures and two to three times for treatment.
The drug should be injected only after the animal has been examined by a specialist.

Analogs

Vitafel Globulin, Vitafel-S are almost complete analogues of Globfel. These drugs are used intramuscularly, subcutaneously or intravenously.

Multifel-4 is indicated for use in the same cases as Globfel-4. However, the principle of action of these drugs is different. The active substances of Multifel are weakened antigens of the above viruses, i.e. It cannot be used to treat sick animals. This drug also has more side effects than Globfel.

Advantages and disadvantages

One of the disadvantages is the inconvenience of transportation - so that the product does not lose its active qualities, the manufacturer recommends transporting Globfel-4 with a cold pack.

The advantages:

Relatively low cost, due to the fact that the developer is located in Moscow and the drug is not exportable.
Efficiency.

Contraindications

Side effects

Possible (but not required) are an increase in body temperature after the injection and the appearance of allergic reactions.

Immunovet 3 in and 3 d

The drug is made from the blood serum of horses that have been injected with the viruses of distemper, hepatitis, adenovirus and canine parvovirus. Globulin is produced in ampoules or bottles of 2; 10; 20 cm3, which corresponds to 1; 5; 10 doses.

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The cost of a dose in June 2022 was 110 rubles.

How to use and what to replace with

The medicine contains antibodies against dangerous viral diseases of dogs. Used for therapeutic purposes when a viral disease is suspected or for prophylaxis when vaccination dates are postponed.

To whom is it assigned?

The drug is used for the treatment and prevention of a dangerous disease in pets – chlamydia.
In the course of numerous studies regarding the pharmaceutical drug "Globfel-4", it was found that its therapeutic activity extends to the following infectious diseases:

Chlamydia. It is a bacterial infection that, after entering the cat’s body, provokes a rise in body temperature, coughing, discharge from the nasal cavity and organ of vision, and also causes the pet to refuse to eat.
Rhinotracheitis. An illness caused by the herpes virus and causing difficulty breathing, rhinitis, impaired bowel movements, swelling of the pharynx and high body temperature.
Calcivirosis. An infectious lesion of the cat's respiratory system, which is characterized by a febrile state of the animal, shortness of breath, apathy, diarrhea, ulcerations on the tongue and nose.
Panleukopenia. Infection of an animal with the FPV paravirus, resulting in the pet vomiting, diarrhea, lethargy and experiencing poor coordination.

Immunomodulators for viral diseases

Immunostimulants are drugs that accelerate the production of special cells that help the body fight infections and viruses. This group includes interferons, live vaccines, interleukins, and peptides. They are used in the treatment of infections caused by bacteria, viruses or fungi, as well as cancer and immunodeficiency.

Immunosuppressants or immunosuppressants are drugs that suppress the activity of lymphocytes and inhibit the functioning of the immune system. These include hormonal agents, some antibiotics, and immunoglobulins. Immunosuppressants in veterinary medicine are used in the treatment of allergies and autoimmune diseases.

Immunosuppressants in veterinary medicine are used only in the treatment of autoimmune pathologies and allergies.

"Ronkoleikin"

The main active ingredient of the immunomodulator for cats is human interleukin-2. The drug also contains the following components: D-mannitol, ammonium carbonate, dodecyl sulfate, dithiothreitol and water for injection. "Ronkoleukin" is available in ampoules of 1 ml and in bottles of 10 ml.

The drug is used not only to treat cats; veterinarians also prescribe it for dogs, fur-bearing animals and even fish. You can administer Roncoleukin to a cat using several methods:

intravenously;
subcutaneously;
orally;
intranasally.

The optimal method is selected by a veterinarian. In some cases, the doctor may recommend injecting the drug directly into the bladder or applying it externally. If the owner administers Roncoleukin to the pet himself, he should not shake the ampoule before drawing the medicine into the syringe.

The treatment regimen is prescribed only by a veterinarian; you cannot administer immunostimulants to cats on your own initiative. Experts do not recommend using Ronkoleukin together with vitamins, antiviral drugs and antibiotics. The drug is not prescribed to animals that have recently been vaccinated. Roncoleukin should not be mixed with glucose. After administration of the drug, the cat may experience swelling at the injection site, which will subside within 48 hours.

General information

Globfel-4 (Globfel-4) is a serum that prevents the cat’s body from being affected by infectious disease viruses and facilitates the course of the disease in infected animals.

The drug is used for the prevention and treatment of the following diseases:

acute respiratory rhinotracheitis;
panleukopenia, or feline distemper;
calicivirus;
chlamydia.

The drug was developed by a Russian company that specializes in producing drugs and vaccines for pets.

Release form and cost

The serum is produced as a clear liquid with a pale yellow tint. The preparation may contain slight turbidity. During long-term storage, slight precipitation may occur, which easily dissolves when shaken.

The serum is packaged in 3 ml glass bottles containing 1 ml of solution, which corresponds to one immune dose.

The shelf life is 2 years from the date of manufacture. The bottles are stored in a cool, dark place at a temperature of 2 to 8 degrees.

Opened, unused packaging should be discarded by first boiling the contents for 15 minutes in a closed container.

Immunomodulators for cats: general information and basic drugs

And only when this influence is really necessary.
And exactly as much as is needed to restore natural defense mechanisms. Modern “intelligent” immunomodulators in veterinary medicine are mandatory:

included in schemes for the prevention and treatment of viral and bacterial infectious diseases (canine distemper, viral enteritis, salmonellosis, etc.), parasitic diseases (helminthiases, demodicosis, etc.), fungal infections (dermatophytoses, etc.);
used in veterinary psychoneurology (stressful conditions in cats and dogs after moving, exhibitions, etc.) and geriatrics (treatment of diseases and immunodeficiency conditions associated with the age of animals);
used in the process of preoperative preparation and postoperative treatment, prescribed in the postpartum period, for vitamin deficiencies and exhaustion.

And this is not a complete list.

The use of immunomodulators in veterinary medicine has not only radically changed established approaches to treating animals, but has also made it possible to significantly reduce the list of diseases traditionally considered incurable or difficult to treat.

The use of immunomodulators for dogs is indicated for the following diseases:

plague, viral enteritis, piroplasmosis (a severe infectious disease that occurs after a tick vector bite) and other infections;

The use of immunomodulators for cats is indicated for the following diseases:

hermatonellosis (infectious anemia), dermatomycosis (ringworm), false rabies and other diseases.

Timely use of immunomodulators gives pets and their owners a chance for a favorable outcome, sometimes even in the most advanced cases.

A separate area of application of immunotherapy is veterinary oncology. Given the seriousness of the diagnosis, the prescription of potent immunostimulants, such as roncoleukin and its analogues, is still practiced here. However, competent veterinary oncologists prefer modern immunomodulatory agents, which are fundamentally different from immunostimulants in their mechanism of action and the absence of side effects and complications.

It is to this group of immunomodulators that Biobran belongs, which in its effectiveness is similar to immunostimulants for emergency use, and at the same time has a high safety profile.

Please note: This article is intended for veterinarians only and should not be used by cat owners to self-treat their pets.

What is Globfel-4

Globfel-4 (Globfel-4) is a drug intended for the prevention and treatment of rhinotracheitis, calcivirosis, chlamydia and plague (panleukopenia). The manufacturer of the serum is Russian.

International nonproprietary name of the drug: globulin against panleukopenia, infectious rhinotracheitis, calicivirus and chlamydia in cats

In what form is the drug available?

Globfel-4 is available in the form of an injection solution. Externally, it is a transparent or opalescent (with a pearlescent tint when exposed to light) liquid; it can be colorless or yellowish. A precipitate may appear in the solution, but upon shaking it disappears (usually this phenomenon occurs during long-term storage).

The serum is poured into glass bottles, closed with a rubber stopper and rolled with a metal ring with the ability to bend. Each vial contains a commercial dose of 1 ml. The bottles are packed in boxes made of transparent polyethylene or cardboard, 10 pieces each. Each package contains instructions for use.

Before purchasing serum, pay attention to the production date and expiration date.

Composition of the drug Globfel-4

The serum contains horse blood globulins, which are active against the viruses of panleukopenia, rhinotracheitis, calcivirus infection and chlamydia.

How to properly store whey

The instructions indicate that Globfel-4 should be stored and transported under the following conditions:

in a dry, dark place;
at temperatures from 2 °C to 8 °C;
in places inaccessible to children;
during two years.

It is convenient to store the serum in the refrigerator in a medicine cabinet with other medications. It is more difficult to transport it. A cooler bag is ideal for this, but it’s inconvenient to take it for one bottle. I usually carry these medications in my purse. I put a small bottle with ice at the bottom (I freeze it in advance). To prevent the medicine from freezing, I place a napkin or towel on the bottle. This method is especially convenient in summer.

If you store Globfel-4 in the refrigerator, then you need to allocate a separate place for this so that the drug does not come into contact with food

Storage conditions

The medicine is stored at low temperatures (from +2...+8°C). The optimal storage location is the bottom shelf of the refrigerator. The medicine should be out of direct sunlight; manufacturers recommend storing the bottles in the manufacturer's packaging along with the attached instructions.

You cannot store the medicine in the freezer, since after freezing and settling, Globfel-4 loses its properties. The shelf life of the medicine remains for two years from the date of release, as evidenced by the date on the packaging.