“Profender” is one of the anthelmintic drugs that have received good recommendations from specialists in veterinary clinics. Instructions for use of the drug "Profender" indicate that it can be used to treat animals of all age groups, regardless of health status.
Helminth infestation is one of the most common diseases found in domestic cats of all breeds. Signs of parasite damage include pet lethargy, refusal to eat as a result of deterioration or complete lack of appetite, decreased immune defense and the development of various types of allergic reactions.
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Composition and release form Bayer Profender Spot-On - Profender for cats
Bayer (Bayer) Profender Spot-On - Profender is a complex anthelmintic drug. Bayer (Bayer) Profender Spot-On - Profender contains emodepside and praziquantel as active ingredients, as well as auxiliary components (butylhydroxyanisole, isopropylidene glycerol, lactic acid). The drug is a transparent solution for external use from yellow to brown, 1 ml of which contains 21.4 mg of emodepside and 85.8 mg of praziquantel. The drug is produced packaged in 0.35; 0.7; 1.12 ml in polypropylene pipettes with caps, packed in 2 pieces in aluminum blisters, placed in cardboard boxes.
Analogues of the drug
The following drugs are analogues of Profender:
- Stronghold;
- IN-AP complex;
- Advocate.
Photo gallery: Analogues of Profender by release form
Stronghold is a complex anthelmintic, the formula of which was developed in the USA (Pfizer Animal Health)
IN-AP drops are a domestic development (NVP Astrapharm), so such drops are inexpensive
Antiparasitic complex drug for cats Advocate is produced by the German company Bayer
Table: comparison of drug analogues
| Name | Release form | Active substance | Action provided | Indications for use | Contraindications | Price |
| Stronghold | Drops for external use | Selamectin | Nematocidal, insecticidal and acaricidal | Nematodes, insects and sarcoptic mites, prevention of dirofilariasis | Young (under 6 weeks), moist or damaged skin | From 300 rubles for 1 pipette |
| IN-AP | Aversectin, fipronil, praziquantel | Insectoacaricidal and anthelmintic | Nematodes and ectoparasites | Age up to 8 weeks, pregnancy and lactation, infectious diseases, weakened condition | From 160 rubles for 1 pipette | |
| Advocate | Imidacloprid, moxidectin | Nematodes, insects and sarcoptic mites, prevention of dirofilariasis | Age up to 9 weeks, weight less than 1 kg, pregnancy and lactation, infectious diseases | From 380 rubles for 1 pipette |
Pharmacological properties
Bayer (Bayer) Profender Spot-On - Profender has a wide spectrum of anthelmintic action on round and tape helminths, including Toxocara cati, Toxascaris leonina, Ancylostoma tubaeforme, Echinococcus multilocularis, Dipylidium caninum, Taenia taeniaeformis, parasitizing cats. Emodepside, which is part of the drug, is a semi-synthetic compound from the group of depsipeptides and has a nematocidal effect. By exerting a stimulating effect on presynaptic latrophilin receptors, emodepside causes paralysis and death of the parasite. The mechanism of action of praziquantel is the depolarization of neuromuscular ganglion blockers, disruption of glucose transport and microturbular function of all phases of cestode development, causing disruption of neuromuscular innervation, paralysis and death of parasites. The pharmacokinetic properties of the drug ensure its good absorption from the site of application and long-term preservation in therapeutic concentrations in the animal’s body. Maximum concentrations of praziquantel and emodepside are observed in the blood serum after 2–4 days; compounds are excreted from the body mainly in urine in unchanged form and partially in metabolized form within 28-30 days. Bayer (Bayer) Profender Spot-On - Based on the degree of impact on the body, Profender is classified as a moderately hazardous substance (hazard class 3 according to GOST 12.1.007-76), in recommended doses it does not have locally irritating, embryotoxic, teratogenic, mutagenic and immunotoxic effects. The drug is well tolerated by cats of different breeds in a therapeutic dose and in a 3-fold therapeutic dose.
Why is deworming necessary?
Deworming is a set of actions and measures that are aimed at ridding an animal of worms and preventing its re-infection. Secondary invasion is more than likely because the development cycle of helminths from egg to adult is about 4 months.
During cat hygiene procedures, the possibility of infection with worms is 100%. Therefore, it is necessary to deworm a cat often - at least 3-4 times a year.
Infection with worms is the most “popular nuisance” even among domestic cats. In fact, this serious problem can cause significant damage to your pet's health.
In the process of development and reproduction, worms feed on the tissues of internal organs, the blood of the animal, disrupt the functioning of the gastrointestinal tract, and undermine the immune system.
An infected cat becomes a source of danger for family members. Children are especially defenseless against helminthic infestations. To protect the family from infection, a domestic cat should be dewormed regularly and not wait for obvious manifestations of the disease.
A few more reasons why it is necessary to worm your pets systematically:
- cats are constantly infected with worms: when they eat raw meat, fish, offal, pick up pieces of food from the floor, and also during cat washing;
- waste from worms poisons the body of an infected cat and undermines its health;
- some worms are able to overcome the placental barrier and infect kittens in utero, this often leads to the birth of weakened offspring or their death;
- infected cats are emaciated, stunted, and suffer from anemia.
Doses and method of administration
Before use, remove the protective cap from the pipette and, positioning it vertically, pierce the protective membrane of the pipette nose (putting the cap on the back side), then remove the cap again. The drug, by spreading the fur, is applied to places inaccessible for licking, directly on the skin between the shoulder blades at the base of the neck. When treating large cats, the contents of the pipettes are applied to the skin in the neck area in several places. The minimum therapeutic dose of Bayer Profender Spot-On is 0.14 ml/kg of animal weight. Deworming of cats using Bayer (Bayer) Profender Spot-On - Profender is carried out starting from 8 weeks of age, in the following doses: Weight of the cat, kg, marking and volume of pipettes used: - from 0.5 to 2.5 "Bayer ( Bayer) Profender Spot-On - Profender for small cats - 0.35 ml;
- from 2.6 to 5 "Bayer (Bayer) Profender Spot-On - Profender for medium cats" - 0.7 ml;
- from 5.1 to 8.0 "Bayer (Bayer) Profender Spot-On - Profender for large cats" - 1.12 ml;
- more than 8.0 - combinations of pipettes of various packaging.
When treating cats weighing more than 8 kg, Bayer Profender Spot-On is used at the rate of 0.14 ml per kg of animal weight, using combinations of pipettes of various packaging. Deworming of cats for therapeutic purposes is carried out according to indications, for preventive purposes - quarterly.
special instructions
When working with Bayer Profender Spot-On - Profender, you should follow the generally accepted rules of personal hygiene and safety precautions provided for working with medicinal products for animals. While working with Bayer Profender Spot-On, Profender is not allowed to smoke, drink or eat. When finished, wash your hands thoroughly with warm water and soap. Do not wash, pet or allow the animal near small children for 24 hours after treatment with the drug. If you accidentally get the drug on your skin or eyes, rinse it off immediately with a stream of water; if it gets inside, consult a doctor. Empty drug pipettes must not be used for household purposes; they are placed in a plastic bag and thrown into a trash container.
Medicines for nematodes or roundworms
Nematodes are worms that have a non-segmented body in the shape of a thread or spindle, round in cross section. The most common parasites in the human body are pinworms, Toxocara, Trichinella, and whipworm. Most varieties of nematodes parasitize the digestive system. Among them, the most common are pinworms and roundworms. Medicines intended for the treatment of nematodes and their analogues:
- Pyrantel pamoate – Nemotsid, Pyrantel, Helmintox, Combantrin;
- Levamisole – Decaris;
- Albendazole – Vormil, Nemozol, Gelmodol-VM (in the form of chewable tablets and suspension);
- Piperazine adipate – Piperazine;
- Pyrvinium embonate – Vanquin, Pyrkon, Pyrivinium;
- Mebendazole – Thermox, Wormin, Vermakar, Vermox, Vero-Mebendazole, Mebex;
- Carbendacim – Medamin.
Nematodes occurring outside the digestive tract are treated with the following tablets:
- Ivermectin - Baymek, Ivermek, Ivomek.
- Diethylcarbamazine – Ditrazine, Ditrazine citrate.
Antihelminthic therapy has a very important feature - deworming tablets are taken in several courses. Most often, two times are enough. This is due to the fact that the active substance of most of these drugs acts only on adult individuals, without affecting their eggs and larvae. In addition, with enterobiasis there are frequent cases of reinvasion (self-infection).
Worms belonging to the group of cestodes are the culprits of a wide range of helminthic infestations: these are alveococcosis, echinococcosis, sparganosis, taeniasis, cysticercosis (pathogen - pork tapeworm), teniarinhoz, coenurosis, taeniasis (pathogen - bovine tapeworm), diphyllobothriasis (pathogen - broad tapeworm) , hymenolepiasis (pathogen - dwarf tapeworm).
Medicines for the treatment of cestodiasis and their analogues:
- Akrikhin (Mepakrin) - used for taeniasis, hymenolepiasis, diphyllobothriasis, giardiasis, leishmaniasis, malaria;
- Niclosamide (Fenasal) - used for invasion by all types of cestodes;
- Albendazole (Nemozol) is used for mixed invasions, including in combination with giardiasis, echinococcosis, neurocysticercosis, and for the treatment of extraintestinal forms of cestodiasis.
